{"created":"2023-06-20T14:15:02.417222+00:00","id":772,"links":{},"metadata":{"_buckets":{"deposit":"4f2d3b00-6e07-4048-9c14-356d12252f11"},"_deposit":{"created_by":3,"id":"772","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"772"},"status":"published"},"_oai":{"id":"oai:niu.repo.nii.ac.jp:00000772","sets":["3:4:19"]},"author_link":["2000","1997","1998","1999"],"item_10_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"292","bibliographicPageStart":"283","bibliographicVolumeNumber":"8","bibliographic_titles":[{"bibliographic_title":"長崎国際大学論叢"},{"bibliographic_title":"Nagasaki International University Review","bibliographic_titleLang":"en"}]}]},"item_10_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"MORINAGA, Osamu"}],"nameIdentifiers":[{"nameIdentifier":"1999","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SHOYAMA, Yukihiro"}],"nameIdentifiers":[{"nameIdentifier":"2000","nameIdentifierScheme":"WEKO"}]}]},"item_10_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10_description_24":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"In this review, we summarize studies from Asian and Caucasian countries and highlight the importance of the APC anticoagulant system in coagulation regulation in vivo. Thrombophilia is defined as an increased tendency to thrombosis, and can be either inherited or acquired. It has been recognized that in Caucasians, a polymorphism of coagulation factor V, factor V Leiden (R506Q), is a major risk factor for venous thrombosis. However, this does not appear to be the case for Asian thrombophilia. Accumulated studies from Asian and Caucasian countries indicate that the frequencies of protein S deficiency and of protein C deficiency were higher in Asian patients suffering from deep vein thrombosis than in Caucasian patients, indicating that deficiency of the activated protein C (APC) anticoagulant system is more common in Asain than in Caucasian patients. This would suggest that these gene variants are responsible for the deficiency of the activated protein C anticoagulant system and that the deficiency of the activated protein C anticoagulant system is a major risk factor for venous thrombosis.","subitem_description_type":"Other"}]},"item_10_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"イースタンブロッティングは TLC で分離した薬用成分を PVDF 膜へ転写し、抗原であるターゲット低分子のモノクローナル抗体で染色する手法で、目で見ることが出来る説得力の大きな手法である。新たに開発したイースタンブロッティングでは親水性ポリエーテルスルホン膜を用いることで、ジンセノシド類を膜上で展開・分離することが可能となり、転写プロセスを省略し、抗体染色が行える。さらに染色結果をスキャナーで取り込み、NIH Image 画像解析ソフトウェアを用いてスポットを数値化し、定量分析を完結させた。HPLC による分析値との相関も良好であった。"}]},"item_10_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"長崎国際大学"}]},"item_10_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11766493"}]},"item_10_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-4094"}]},"item_10_subject_25":{"attribute_name":"Keyword","attribute_value_mlt":[{"subitem_subject":"Eastern blotting, Polyethersulphone membrane chromatography, Ginsenosides, NIH Image software","subitem_subject_scheme":"Other"}]},"item_10_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"森永, 紀"},{"creatorName":"ﾓﾘﾅｶﾞ, ｵｻﾑ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"正山, 征洋"},{"creatorName":"ｼｮｳﾔﾏ, ﾕｷﾋﾛ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-05-16"}],"displaytype":"detail","filename":"RN08-027.pdf","filesize":[{"value":"490.1 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"RN08-027","url":"https://niu.repo.nii.ac.jp/record/772/files/RN08-027.pdf"},"version_id":"61daa533-9c38-498c-bd54-83632892e534"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"イースタンブロッティング"},{"subitem_subject":"ポリエーテルスルホン膜分離展開"},{"subitem_subject":"ジンセノシド類"},{"subitem_subject":"NIH Image 画像解析ソフトウェア"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper"}]},"item_title":"薬用人参成分のイースタンブロッティング","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"薬用人参成分のイースタンブロッティング"},{"subitem_title":"Eastern Blotting Technique for Ginseng Saponins","subitem_title_language":"en"}]},"item_type_id":"10","owner":"3","path":["19"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-04-01"},"publish_date":"2015-04-01","publish_status":"0","recid":"772","relation_version_is_last":true,"title":["薬用人参成分のイースタンブロッティング"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-07-21T06:18:03.297531+00:00"}