{"created":"2023-06-20T14:15:06.967852+00:00","id":851,"links":{},"metadata":{"_buckets":{"deposit":"41e4b98c-3f3b-43db-9b7c-ac4e3baef2d5"},"_deposit":{"created_by":3,"id":"851","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"851"},"status":"published"},"_oai":{"id":"oai:niu.repo.nii.ac.jp:00000851","sets":["3:4:24"]},"author_link":["2395","2396"],"item_10_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"143","bibliographicPageStart":"133","bibliographicVolumeNumber":"13","bibliographic_titles":[{"bibliographic_title":"長崎国際大学論叢"},{"bibliographic_title":"Nagasaki International University Review","bibliographic_titleLang":"en"}]}]},"item_10_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"SHOYAMA, Yukihiro"}],"nameIdentifiers":[{"nameIdentifier":"2396","nameIdentifierScheme":"WEKO"}]}]},"item_10_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10_description_24":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"Japanese traditional medicine(JTM)was originated from Chinese medicine that was go back to 2000 years ago or more of history. Among JTM licorice is the most important crude medicine because 70% of JTM prescribe licorice. Therefore, licorice will be focused in this review. The scientific name of licorice is Glycyrrhiza species like G. uralensis and G. glabra. Since glycyrrhizin which has been widely used as medicines, food additives, and sweeteners is contained in only Glycyrrhiza species, a large number of wild licorice has been collecting in the world promoting desertation which brings the shortage of licorice widely. In order to conquer the shortage of licorice, a trial breeding investigation by analysis of higher concentration of glycyrrhizin contained in G. uralensis seedlings and the propagation of them have been started. Furthermore, a missile type molecular breeding of G. uralensis containing higher concentration of glycyrrhizin using compact gene of anti-glycyrrhizin monoclonal antibody has been investigated.","subitem_description_type":"Other"}]},"item_10_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"本総説では70%の漢方処方に配合される甘草についての歴史的背景､重要性､植物学的考察､資源の供給情況､資源の枯渇に至った経緯等を検証した｡日本薬局方には G. uralensis(ｳﾗﾙｶﾝｿﾞｳ)と G. glabra(ｽﾍﾟｲﾝｶﾝｿﾞｳ)が収載される｡これらのうち生産量､流通量とも多いｳﾗﾙｶﾝｿﾞｳについて言及した｡ｳﾗﾙｶﾝｿﾞｳは多年生草本で､初夏から夏にかけて総状花序に蝶花を開き特徴ある果実を結ぶ｡甘草の薬理活性に関わる記述は2千年前の神農本草経やﾃﾞｲｵｽｺﾘﾃﾞｽに記され､歴史を追って記述され今日に至っている｡近年の甘草の需給ﾊﾞﾗﾝｽを見ると､最大生産国であり使用国である中国において､直近では需要量に対して約半分の供給量となっている｡また､甘草の枯渇が懸念されているが､これは甘草の乱獲によるもので更に砂漠化を惹起しているとの見解が出されている｡これらの情況を受けて､ﾓﾝｺﾞﾙ内の遺伝子変異の少ない地域から種子を導入し､選抜育種を行いｸﾞﾘﾁﾙﾘﾁﾝ高含量株の特定を行い､ｸﾛｰﾝ増殖による均質な品種の作出を行なっている｡又､ﾐｻｲﾙﾀｲﾌﾟの分子育種と命名した､抗ｸﾞﾘﾁﾙﾘﾁﾝﾓﾉｸﾛｰﾅﾙ抗体の小型化抗体遺伝子を培養甘草に形質導入し､ｸﾞﾘﾁﾙﾘﾁﾝ含量を上昇させる品種の作出を行なっているので､これらについても紹介した｡"}]},"item_10_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"長崎国際大学"}]},"item_10_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11766493"}]},"item_10_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-4094"}]},"item_10_subject_25":{"attribute_name":"Keyword","attribute_value_mlt":[{"subitem_subject":"Japanese traditional medicine, licorice, glycyrrhizin, Glycyrrhiza species, breeding, missile type molecular breeding","subitem_subject_scheme":"Other"}]},"item_10_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"正山, 征洋"},{"creatorName":"ｼｮｳﾔﾏ, ﾕｷﾋﾛ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-05-14"}],"displaytype":"detail","filename":"RN13-014.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"RN13-014","url":"https://niu.repo.nii.ac.jp/record/851/files/RN13-014.pdf"},"version_id":"f278c30d-670d-42c0-befb-5399037df313"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"漢方"},{"subitem_subject":"甘草"},{"subitem_subject":"ｸﾞﾘﾁﾙﾘﾁﾝ"},{"subitem_subject":"ｸﾞﾘﾁﾙﾘｰｻﾞ属植物"},{"subitem_subject":"育種"},{"subitem_subject":"ﾐｻｲﾙﾀｲﾌﾟ分子育種"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper"}]},"item_title":"漢方薬資源のなかの甘草の枯渇克服を目指して -漢方薬の危機管理-","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"漢方薬資源のなかの甘草の枯渇克服を目指して -漢方薬の危機管理-"},{"subitem_title":"Overcoming the Shortage of licorice for Japanese Traditional Medicine: Risk Management for Japanese Traditional Medicine","subitem_title_language":"en"}]},"item_type_id":"10","owner":"3","path":["24"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-04-01"},"publish_date":"2015-04-01","publish_status":"0","recid":"851","relation_version_is_last":true,"title":["漢方薬資源のなかの甘草の枯渇克服を目指して -漢方薬の危機管理-"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-07-21T06:15:28.751232+00:00"}