{"created":"2023-06-20T14:15:09.638534+00:00","id":922,"links":{},"metadata":{"_buckets":{"deposit":"163445d3-88e5-4fdc-ad85-1359cf189607"},"_deposit":{"created_by":3,"id":"922","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"922"},"status":"published"},"_oai":{"id":"oai:niu.repo.nii.ac.jp:00000922","sets":["3:4:35"]},"author_link":["2825","2831","2824","2823","2830","2834","2829","2833","2827","2828","2826","2832"],"item_10_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015-03","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"166","bibliographicPageStart":"157","bibliographicVolumeNumber":"15","bibliographic_titles":[{"bibliographic_title":"長崎国際大学論叢"},{"bibliographic_title":"Nagasaki International University Review","bibliographic_titleLang":"en"}]}]},"item_10_creator_3":{"attribute_name":"著者別名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"EHARA, Tsuguhisa"}],"nameIdentifiers":[{"nameIdentifier":"2829","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"SAKAMOTO, Shun"}],"nameIdentifiers":[{"nameIdentifier":"2830","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"URAKAWA, Yuya"}],"nameIdentifiers":[{"nameIdentifier":"2831","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"ISHII, Kensuke"}],"nameIdentifiers":[{"nameIdentifier":"2832","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"TANAKA, Chisato"}],"nameIdentifiers":[{"nameIdentifier":"2833","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"YANAGIMOTO, Kotomi"}],"nameIdentifiers":[{"nameIdentifier":"2834","nameIdentifierScheme":"WEKO"}]}]},"item_10_description_19":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_10_description_24":{"attribute_name":"Abstract","attribute_value_mlt":[{"subitem_description":"The Yagi's perfusion system has widely been used to study the beats of excised frog heart. Here, we describe a new method to obtain a measure of cardiac output of the frog heart perfused with the Yagi's system. In the new method, the changes in ventricular volume during systole and diastole are converted to the changes in air pressure by using the communicating vessel chamber in which the tissue chamber bathing the ventricle is connected via a communicating tube to the air-tight chamber for pressure detection. With this method, the Frank-Starling mechanism associated with the changes in preload is clearly demonstrable. With an additional apparatus to increase the hydrostatic pressure within the aorta, it is possible to show the unique changes in ventricular dynamics accompanying the increases in afterload. In addition, a method to stably record the ECG simultaneously with the above measurement is described. Our new methods may be useful for the student practice in which students should learn the physiological as well as pharmacological properties of heart.","subitem_description_type":"Other"}]},"item_10_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"伝統的な生理学実習項目の一つであるｶｴﾙ心臓の八木式灌流実験法に改良を加え､心室拍動をより定量的に観察記録できるようにした｡すなわち､収縮･拡張ｻｲｸﾙ中の心室の容積変化を気圧変化に変換して捉える簡便な装置(連通標本槽)を考案し､圧変化を拍出量の指標として連続描記できるようにした｡連通標本槽は心室を浸す槽と圧変化を発生する気密な槽とを連結したものである｡この方法により､前負荷の増減に適応する心拍出量の増減､すなわちﾌﾗﾝｸ･ｽﾀｰﾘﾝｸﾞ機構を明確に示すことができる｡また､大動脈内静水圧を増加させる装置を考案した｡これを用いることにより､後負荷増加に対応する心室拍動動態のﾕﾆｰｸな変化を観察できる｡さらに､この実験系における心電図の安定した記録法を考案した｡これにより心臓の機械的活動と電気的活動とを同時に対応させることができる｡われわれの新しい実験方法は､学生実習において学生に心臓の生理学･薬理学的性質を学ばせるために大変有用であろう｡"}]},"item_10_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"長崎国際大学"}]},"item_10_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11766493"}]},"item_10_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-4094"}]},"item_10_subject_25":{"attribute_name":"Keyword","attribute_value_mlt":[{"subitem_subject":"Yagi's perfusion method, Frog heart, Cardiac output, Frank-Starling mechanism, ECG","subitem_subject_scheme":"Other"}]},"item_10_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"頴原, 嗣尚"},{"creatorName":"ｴﾊﾗ, ﾂｸﾞﾋｻ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"坂元, 駿"},{"creatorName":"ｻｶﾓﾄ, ｼｭﾝ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"浦川, 勇哉"},{"creatorName":"ｳﾗｶﾜ, ﾕｳﾔ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"石井, 賢介"},{"creatorName":"ｲｼｲ, ｹﾝｽｹ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"田中, 千智"},{"creatorName":"ﾀﾅｶ, ﾁｻﾄ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"栁本, 琴美"},{"creatorName":"ﾔﾅｷﾞﾓﾄ, ｺﾄﾐ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-05-14"}],"displaytype":"detail","filename":"RN15-014.pdf","filesize":[{"value":"934.0 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"RN15-014","url":"https://niu.repo.nii.ac.jp/record/922/files/RN15-014.pdf"},"version_id":"13e708b2-1afa-40b1-800c-81dc09ca1f25"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"八木式灌流法"},{"subitem_subject":"ｶｴﾙ心臓"},{"subitem_subject":"心拍出量"},{"subitem_subject":"ﾌﾗﾝｸ･ｽﾀｰﾘﾝｸﾞ機構"},{"subitem_subject":"心電図"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper"}]},"item_title":"ｶｴﾙ心臓八木式灌流法の定量的実験への改良 ―心拍出量測定から心電図同時記録まで―","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ｶｴﾙ心臓八木式灌流法の定量的実験への改良 ―心拍出量測定から心電図同時記録まで―"},{"subitem_title":"The Yagi's Perfusion Method for Frog Heart Improved to Enable Quantitative Experiments: From the Measurement of Cardiac Output to Simultaneous ECG Recording","subitem_title_language":"en"}]},"item_type_id":"10","owner":"3","path":["35"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-04-01"},"publish_date":"2015-04-01","publish_status":"0","recid":"922","relation_version_is_last":true,"title":["ｶｴﾙ心臓八木式灌流法の定量的実験への改良 ―心拍出量測定から心電図同時記録まで―"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-07-21T06:14:25.690613+00:00"}